BDBM50073845 (4-Benzyl-benzyl)-[2-(1-hydroxymethyl-2,2-dimethyl-propylcarbamoyl)-4-methyl-pentyl]-phosphinic acid::CHEMBL24628

SMILES: CC(C)CC(CP(O)(=O)Cc1ccc(Cc2ccccc2)cc1)C(=O)NC(CO)C(C)(C)C

InChI Key: InChIKey=QEJJWFRQRSNLSQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50073845   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50073845 ((4-Benzyl-benzyl)-[2-(1-hydroxymethyl-2,2-dimethyl...) Show SMILES CC(C)CC(CP(O)(=O)Cc1ccc(Cc2ccccc2)cc1)C(=O)NC(CO)C(C)(C)C Show InChI InChI=1S/C27H40NO4P/c1-20(2)15-24(26(30)28-25(17-29)27(3,4)5)19-33(31,32)18-23-13-11-22(12-14-23)16-21-9-7-6-8-10-21/h6-14,20,24-25,29H,15-19H2,1-5H3,(H,28,30)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibitory activity against recombinant matrix metalloprotease-1 (MMP-1).				Bioorg Med Chem Lett 9: 127-32 (1999) BindingDB Entry DOI: 10.7270/Q2JD4VZ4
					More data for this Ligand-Target Pair