BDBM50073919 CHEMBL3409462

SMILES: Nc1ccc(cc1Cl)C(=O)N1CCC(CC1)N1CCCCC1

InChI Key: InChIKey=PBRYPNLRVJCUEN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50073919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM50073919 (CHEMBL3409462) Show SMILES Nc1ccc(cc1Cl)C(=O)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C17H24ClN3O/c18-15-12-13(4-5-16(15)19)17(22)21-10-6-14(7-11-21)20-8-2-1-3-9-20/h4-5,12,14H,1-3,6-11,19H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	654	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of LRRK2 G2019S mutant (1326 to 252 aa) (unknown origin) stably expressed in HEK293 cell lysate using [gamma-32P] after 15 mins by Cerenko...				Eur J Med Chem 95: 29-34 (2015) Article DOI: 10.1016/j.ejmech.2015.03.003 BindingDB Entry DOI: 10.7270/Q2TH8PDX
					More data for this Ligand-Target Pair