BDBM50073931 CHEMBL3409472

SMILES: Cc1ccc(Nc2ccc(cc2Cl)C(=O)N2CCC(CC2)N2CCCCC2)cc1

InChI Key: InChIKey=GDPTWGDVNPVHNF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50073931   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM50073931 (CHEMBL3409472) Show SMILES Cc1ccc(Nc2ccc(cc2Cl)C(=O)N2CCC(CC2)N2CCCCC2)cc1 Show InChI InChI=1S/C24H30ClN3O/c1-18-5-8-20(9-6-18)26-23-10-7-19(17-22(23)25)24(29)28-15-11-21(12-16-28)27-13-3-2-4-14-27/h5-10,17,21,26H,2-4,11-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of LRRK2 G2019S mutant (1326 to 252 aa) (unknown origin) stably expressed in HEK293 cell lysate using [gamma-32P] after 15 mins by Cerenko...				Eur J Med Chem 95: 29-34 (2015) Article DOI: 10.1016/j.ejmech.2015.03.003 BindingDB Entry DOI: 10.7270/Q2TH8PDX
					More data for this Ligand-Target Pair