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BDBM50074049 3-((S)-1-Benzyloxycarbonyl-3-methyl-butylcarbamoyl)-aziridine-2-carboxylic acid ethyl ester::CHEMBL152803

SMILES: CCOC(=O)C1NC1C(=O)N[C@@H](CC(C)C)C(=O)OCc1ccccc1

InChI Key: InChIKey=WBOFUGRDYWLSCL-FHERZECASA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074049   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Pro-cathepsin H


(Homo sapiens (Human))
BDBM50074049
PNG
(3-((S)-1-Benzyloxycarbonyl-3-methyl-butylcarbamoyl...)
Show SMILES CCOC(=O)C1NC1C(=O)N[C@@H](CC(C)C)C(=O)OCc1ccccc1
Show InChI InChI=1S/C19H26N2O5/c1-4-25-19(24)16-15(21-16)17(22)20-14(10-12(2)3)18(23)26-11-13-8-6-5-7-9-13/h5-9,12,14-16,21H,4,10-11H2,1-3H3,(H,20,22)/t14-,15?,16?/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.60E+5n/an/an/an/an/an/an/an/a



Albert-Ludwigs-University of Freiburg

Curated by ChEMBL


Assay Description
Inhibition constant for the non time dependent inhibition of cathepsin H


J Med Chem 42: 560-72 (1999)


Article DOI: 10.1021/jm981061z
BindingDB Entry DOI: 10.7270/Q2M907TZ
More data for this
Ligand-Target Pair