BDBM50074121 CHEMBL3409886

SMILES: COc1ccc(NC(=O)C(=O)Nc2ccccc2OC)c(c1)C(=O)Nc1ccc(cc1)N1CCOCC1=O

InChI Key: InChIKey=RRVVZVNUEATOJW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074121   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50074121 (CHEMBL3409886) Show SMILES COc1ccc(NC(=O)C(=O)Nc2ccccc2OC)c(c1)C(=O)Nc1ccc(cc1)N1CCOCC1=O Show InChI InChI=1S/C27H26N4O7/c1-36-19-11-12-21(29-26(34)27(35)30-22-5-3-4-6-23(22)37-2)20(15-19)25(33)28-17-7-9-18(10-8-17)31-13-14-38-16-24(31)32/h3-12,15H,13-14,16H2,1-2H3,(H,28,33)(H,29,34)(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	828	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human factor 10a using acromogenic substrate S-2222 preincubated for 30 mins before substrate addition measured after 20 mins by spectr...				Eur J Med Chem 95: 388-99 (2015) Article DOI: 10.1016/j.ejmech.2015.03.052 BindingDB Entry DOI: 10.7270/Q29G5PH4
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