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SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)NCc1cccnc1

InChI Key: InChIKey=GRERUUFJINNZMA-SFTDATJTSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074256   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50074256
PNG
(CHEMBL159974 | Phosphoric acid mono-[4-((S)-2-acet...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)NCc1cccnc1
Show InChI InChI=1S/C23H31N4O7P/c1-15(2)11-20(22(29)25-14-18-5-4-10-24-13-18)27-23(30)21(26-16(3)28)12-17-6-8-19(9-7-17)34-35(31,32)33/h4-10,13,15,20-21H,11-12,14H2,1-3H3,(H,25,29)(H,26,28)(H,27,30)(H2,31,32,33)/t20-,21-/m0/s1
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PC sid
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Similars
Article
PubMed
n/an/an/a 3.40E+4n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity of the compound against p56 Lck tyrosine kinase SH2 domain was measured using glutathione S-transferase (GST) fusion protein

J Med Chem 42: 722-9 (1999)


Article DOI: 10.1021/jm980612i
BindingDB Entry DOI: 10.7270/Q2Q23ZDX
More data for this
Ligand-Target Pair