BDBM50074279 (2-Morpholin-4-yl-ethyl)-(6-phenyl-pyridazin-3-yl)-amine; hydrochloride::CHEMBL151417::CHEMBL544887

SMILES: C(CN1CCOCC1)Nc1ccc(nn1)-c1ccccc1

InChI Key: InChIKey=GWGMHVNYPVDVIJ-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50074279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50074279 ((2-Morpholin-4-yl-ethyl)-(6-phenyl-pyridazin-3-yl)...) Show SMILES C(CN1CCOCC1)Nc1ccc(nn1)-c1ccccc1 Show InChI InChI=1S/C16H20N4O/c1-2-4-14(5-3-1)15-6-7-16(19-18-15)17-8-9-20-10-12-21-13-11-20/h1-7H,8-13H2,(H,17,19)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1				Bioorg Med Chem Lett 2: 833-838 (1992) Article DOI: 10.1016/S0960-894X(00)80540-5 BindingDB Entry DOI: 10.7270/Q2JQ10ZR
					More data for this Ligand-Target Pair
Acetylcholinesterase (Tetronarce californica (Pacific electric ray) (Tor...)	BDBM50074279 ((2-Morpholin-4-yl-ethyl)-(6-phenyl-pyridazin-3-yl)...) Show SMILES C(CN1CCOCC1)Nc1ccc(nn1)-c1ccccc1 Show InChI InChI=1S/C16H20N4O/c1-2-4-14(5-3-1)15-6-7-16(19-18-15)17-8-9-20-10-12-21-13-11-20/h1-7H,8-13H2,(H,17,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur Curated by ChEMBL					Assay Description In vitro inhibition of Torpedo californica acetylcholinesterase.				J Med Chem 42: 730-41 (1999) Article DOI: 10.1021/jm981101z BindingDB Entry DOI: 10.7270/Q26M37JW
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50074279 ((2-Morpholin-4-yl-ethyl)-(6-phenyl-pyridazin-3-yl)...) Show SMILES C(CN1CCOCC1)Nc1ccc(nn1)-c1ccccc1 Show InChI InChI=1S/C16H20N4O/c1-2-4-14(5-3-1)15-6-7-16(19-18-15)17-8-9-20-10-12-21-13-11-20/h1-7H,8-13H2,(H,17,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur Curated by ChEMBL					Assay Description In vitro inhibition of acetylcholinesterase in homogenized rat striatum.				J Med Chem 42: 730-41 (1999) Article DOI: 10.1021/jm981101z BindingDB Entry DOI: 10.7270/Q26M37JW
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50074279 ((2-Morpholin-4-yl-ethyl)-(6-phenyl-pyridazin-3-yl)...) Show SMILES C(CN1CCOCC1)Nc1ccc(nn1)-c1ccccc1 Show InChI InChI=1S/C16H20N4O/c1-2-4-14(5-3-1)15-6-7-16(19-18-15)17-8-9-20-10-12-21-13-11-20/h1-7H,8-13H2,(H,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of AChE				Eur J Med Chem 45: 1167-72 (2010) Article DOI: 10.1016/j.ejmech.2009.12.038 BindingDB Entry DOI: 10.7270/Q25H7GFM
					More data for this Ligand-Target Pair