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SMILES: CCN(CC)c1cc(C)nc(n1)N(CC)c1c(Cl)cc(OC)cc1Cl

InChI Key: InChIKey=FKDBXJHUAYIUEU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074342   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50074342
PNG
(CHEMBL354584 | N*2*-(2,6-Dichloro-4-methoxy-phenyl...)
Show SMILES CCN(CC)c1cc(C)nc(n1)N(CC)c1c(Cl)cc(OC)cc1Cl
Show InChI InChI=1S/C18H24Cl2N4O/c1-6-23(7-2)16-9-12(4)21-18(22-16)24(8-3)17-14(19)10-13(25-5)11-15(17)20/h9-11H,6-8H2,1-5H3
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Article
PubMed
 15n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant corticotropin releasing factor receptor 1

J Med Chem 42: 805-18 (1999)


Article DOI: 10.1021/jm980222w
BindingDB Entry DOI: 10.7270/Q29S1Q63
More data for this
Ligand-Target Pair