BDBM50074375 CHEMBL354395::N,N-Bis-cyclopropylmethyl-N'-(4-dimethylamino-2-trifluoromethyl-phenyl)-N'-ethyl-6-methyl-[1,3,5]triazine-2,4-diamine

SMILES: CCN(c1nc(C)nc(n1)N(CC1CC1)CC1CC1)c1ccc(cc1C(F)(F)F)N(C)C

InChI Key: InChIKey=MQYHFKHWGJFMLC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074375 (CHEMBL354395 | N,N-Bis-cyclopropylmethyl-N'-(4-dim...) Show SMILES CCN(c1nc(C)nc(n1)N(CC1CC1)CC1CC1)c1ccc(cc1C(F)(F)F)N(C)C Show InChI InChI=1S/C23H31F3N6/c1-5-32(20-11-10-18(30(3)4)12-19(20)23(24,25)26)22-28-15(2)27-21(29-22)31(13-16-6-7-16)14-17-8-9-17/h10-12,16-17H,5-9,13-14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair