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SMILES: COCCN(CCOC)c1nc(C)nc2n(nnc12)-c1ccc(Br)cc1Br

InChI Key: InChIKey=RXOLIHRNNSQJCZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074486   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50074486
PNG
(CHEMBL169955 | [3-(2,4-Dibromo-phenyl)-5-methyl-3H...)
Show SMILES COCCN(CCOC)c1nc(C)nc2n(nnc12)-c1ccc(Br)cc1Br
Show InChI InChI=1S/C17H20Br2N6O2/c1-11-20-16(24(6-8-26-2)7-9-27-3)15-17(21-11)25(23-22-15)14-5-4-12(18)10-13(14)19/h4-5,10H,6-9H2,1-3H3
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Article
PubMed
 7.40n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells

J Med Chem 42: 833-48 (1999)


Article DOI: 10.1021/jm980224g
BindingDB Entry DOI: 10.7270/Q2610ZGP
More data for this
Ligand-Target Pair