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SMILES: COCC(COC)Oc1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C

InChI Key: InChIKey=WUNNHRFQZFKSJM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074498   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50074498
PNG
(3-(2-Bromo-4-isopropyl-phenyl)-7-(2-methoxy-1-meth...)
Show SMILES COCC(COC)Oc1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C
Show InChI InChI=1S/C19H24BrN5O3/c1-11(2)13-6-7-16(15(20)8-13)25-18-17(23-24-25)19(22-12(3)21-18)28-14(9-26-4)10-27-5/h6-8,11,14H,9-10H2,1-5H3
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Article
PubMed
 7.10n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells

J Med Chem 42: 833-48 (1999)


Article DOI: 10.1021/jm980224g
BindingDB Entry DOI: 10.7270/Q2610ZGP
More data for this
Ligand-Target Pair