Found 7 hits for monomerid = 50074744 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50074744
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)Show InChI InChI=1S/C16H12ClNO3/c1-21-11-6-13-15(14(19)7-11)16(20)12(8-18-13)9-3-2-4-10(17)5-9/h2-8,19H,1H3,(H,18,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description Inhibition of Platelet-derived growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this Ligand-Target Pair | |
Protein kinase C alpha type
(Homo sapiens (Human)) | BDBM50074744
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)Show InChI InChI=1S/C16H12ClNO3/c1-21-11-6-13-15(14(19)7-11)16(20)12(8-18-13)9-3-2-4-10(17)5-9/h2-8,19H,1H3,(H,18,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description Inhibition of Protein kinase C alpha |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074744
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)Show InChI InChI=1S/C16H12ClNO3/c1-21-11-6-13-15(14(19)7-11)16(20)12(8-18-13)9-3-2-4-10(17)5-9/h2-8,19H,1H3,(H,18,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description Inhibition of Epidermal growth factor receptor |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Mus musculus) | BDBM50074744
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)Show InChI InChI=1S/C16H12ClNO3/c1-21-11-6-13-15(14(19)7-11)16(20)12(8-18-13)9-3-2-4-10(17)5-9/h2-8,19H,1H3,(H,18,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description Inhibition of EGF-dependent mouse keratinocyte MK cell proliferation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074744
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)Show InChI InChI=1S/C16H12ClNO3/c1-21-11-6-13-15(14(19)7-11)16(20)12(8-18-13)9-3-2-4-10(17)5-9/h2-8,19H,1H3,(H,18,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50074744
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)Show InChI InChI=1S/C16H12ClNO3/c1-21-11-6-13-15(14(19)7-11)16(20)12(8-18-13)9-3-2-4-10(17)5-9/h2-8,19H,1H3,(H,18,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description Inhibition of p60 c-Src tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1/ABL2
(Homo sapiens (Human)) | BDBM50074744
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)Show InChI InChI=1S/C16H12ClNO3/c1-21-11-6-13-15(14(19)7-11)16(20)12(8-18-13)9-3-2-4-10(17)5-9/h2-8,19H,1H3,(H,18,20) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description Inhibition of v-Abl tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this Ligand-Target Pair | |