BindingDB PrimarySearch

BDBM50074832 CHEMBL156605

SMILES: O=C(CN1c2ccccc2N(c2ccccc2)C(=O)C(NC(=O)Nc2ccccc2)C1=O)Nc1ccccc1

InChI Key: InChIKey=PDWDMFQEOPBNJU-UHFFFAOYSA-N

Data: 17 IC50 4 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50074832
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]BDZ1 from CCK2R (unknown origin) expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Activity at CCK1R (unknown origin) expressed in CHO cells assessed as stimulation of intracellular calcium responses				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	541	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]CCK from CCK1R (unknown origin) expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 10 nM (Rvb = 7 to 14 pM...				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 100 nM (Rvb = 7 to 14 p...				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 1000 nM (Rvb = 7 to 14 ...				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	259	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]BDZ1 from CCK1R TM3 (unknown origin) containing T3.28V, T3.29S chimeric mutant expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]BDZ1 from CCK1R TM6 (unknown origin) containing 16.51V, F6.52Y chimeric mutant expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	505	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]BDZ1 from CCK1R TM7 (unknown origin) containing L7.39H chimeric mutant expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]CCK from CCK1R TM2 (unknown origin) containing N2.61T chimeric mutant expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]CCK from CCK1R TM3 (unknown origin) containing T3.28V, T3.29S chimeric mutant expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	317	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]CCK from CCK1R TM6 (unknown origin) containing 16.51V, F6.52Y chimeric mutant expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	303	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]CCK from CCK1R TM7 (unknown origin) containing L7.39H chimeric mutant expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]BDZ2 from CCK2R TM3 (unknown origin) containing T3.28V, T3.29S chimeric mutant expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]BDZ2 from CCK2R TM6 (unknown origin) containing 16.51V, F6.52Y chimeric mutant expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]BDZ2 from CCK2R TM7 (unknown origin) containing L7.39H chimeric mutant expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]CCK from CCK2R TM2 (unknown origin) containing N2.61T chimeric mutant expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]CCK from CCK2R TM3 (unknown origin) containing T3.28V, T3.29S chimeric mutant expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]CCK from CCK2R TM6 (unknown origin) containing 16.51V, F6.52Y chimeric mutant expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]CCK from CCK2R TM7 (unknown origin) containing L7.39H chimeric mutant expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50074832 (CHEMBL156605) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Curated by ChEMBL					Assay Description Displacement of [125I]CCK from CCK2R (unknown origin) expressed in CHO cells				Bioorg Med Chem Lett 25: 1849-55 (2015) Article DOI: 10.1016/j.bmcl.2015.03.051 BindingDB Entry DOI: 10.7270/Q2SJ1NB0
Mayo Clinic Curated by ChEMBL					More data for this Ligand-Target Pair