BDBM50075001 4-(3-Imidazol-1-ylmethyl-indol-1-ylmethyl)-benzonitrile::CHEMBL324326

SMILES: N#Cc1ccc(Cn2cc(Cn3ccnc3)c3ccccc23)cc1

InChI Key: InChIKey=LKHFSKLZJGUKJE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50075001   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50075001 (4-(3-Imidazol-1-ylmethyl-indol-1-ylmethyl)-benzoni...) Show SMILES N#Cc1ccc(Cn2cc(Cn3ccnc3)c3ccccc23)cc1 Show InChI InChI=1S/C20H16N4/c21-11-16-5-7-17(8-6-16)12-24-14-18(13-23-10-9-22-15-23)19-3-1-2-4-20(19)24/h1-10,14-15H,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Nantes Curated by ChEMBL					Assay Description In vitro inhibition of human Cytochrome P450 19A1				Bioorg Med Chem Lett 9: 333-6 (1999) BindingDB Entry DOI: 10.7270/Q20C4TXZ
					More data for this Ligand-Target Pair