BDBM50075009 1-Ethyl-5-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]-1H-indole::1-ethyl-5-((4-fluorophenyl)(1H-imidazol-1-yl)methyl)-1H-indole::CHEMBL41761

SMILES: CCn1ccc2cc(ccc12)C(c1ccc(F)cc1)n1ccnc1

InChI Key: InChIKey=OTIGTACSUNMYAA-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50075009 (1-Ethyl-5-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]...) Show SMILES CCn1ccc2cc(ccc12)C(c1ccc(F)cc1)n1ccnc1 Show InChI InChI=1S/C20H18FN3/c1-2-23-11-9-16-13-17(5-8-19(16)23)20(24-12-10-22-14-24)15-3-6-18(21)7-4-15/h3-14,20H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Nantes Curated by ChEMBL					Assay Description In vitro inhibition of human Cytochrome P450 19A1				Bioorg Med Chem Lett 9: 333-6 (1999) BindingDB Entry DOI: 10.7270/Q20C4TXZ
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50075009 (1-Ethyl-5-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]...) Show SMILES CCn1ccc2cc(ccc12)C(c1ccc(F)cc1)n1ccnc1 Show InChI InChI=1S/C20H18FN3/c1-2-23-11-9-16-13-17(5-8-19(16)23)20(24-12-10-22-14-24)15-3-6-18(21)7-4-15/h3-14,20H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
American University of Ras Al Khaimah Curated by ChEMBL					Assay Description Inhibition of aromatase (unknown origin)				Eur J Med Chem 102: 375-86 (2015) BindingDB Entry DOI: 10.7270/Q2ZC84Q6
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50075009 (1-Ethyl-5-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]...) Show SMILES CCn1ccc2cc(ccc12)C(c1ccc(F)cc1)n1ccnc1 Show InChI InChI=1S/C20H18FN3/c1-2-23-11-9-16-13-17(5-8-19(16)23)20(24-12-10-22-14-24)15-3-6-18(21)7-4-15/h3-14,20H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Nantes University Curated by ChEMBL					Assay Description Inhibition of CYP19				Bioorg Med Chem Lett 16: 1134-7 (2006) Article DOI: 10.1016/j.bmcl.2005.11.099 BindingDB Entry DOI: 10.7270/Q2B27TV6
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50075009 (1-Ethyl-5-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]...) Show SMILES CCn1ccc2cc(ccc12)C(c1ccc(F)cc1)n1ccnc1 Show InChI InChI=1S/C20H18FN3/c1-2-23-11-9-16-13-17(5-8-19(16)23)20(24-12-10-22-14-24)15-3-6-18(21)7-4-15/h3-14,20H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
UFR des Sciences Pharmaceutiques Curated by ChEMBL					Assay Description Inhibition of cytochrome P450 19A1 of human placental microsomes with [1beta,2beta-3H]testosterone				Bioorg Med Chem Lett 13: 1553-5 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HB7
					More data for this Ligand-Target Pair