BDBM50075114 1,1-dimethyl-2-phenylcarboxamidooctanoic anhydride::CHEMBL424453
SMILES: CCCCCC(NC(=O)c1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CCCCC)NC(=O)c1ccccc1
InChI Key: InChIKey=WYMWGQYFGRDOEW-UHFFFAOYSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pancreatic elastase (Sus scrofa) | BDBM50075114 (1,1-dimethyl-2-phenylcarboxamidooctanoic anhydride...) | MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Steel Corporation Curated by ChEMBL | Assay Description Inhibitory activity against porcine pancreatic elastase (PPE) | Bioorg Med Chem Lett 9: 413-8 (1999) BindingDB Entry DOI: 10.7270/Q2BK1BGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin G (Homo sapiens (Human)) | BDBM50075114 (1,1-dimethyl-2-phenylcarboxamidooctanoic anhydride...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Steel Corporation Curated by ChEMBL | Assay Description Inhibitory activity against human leukocyte cathepsin G (h-CG) | Bioorg Med Chem Lett 9: 413-8 (1999) BindingDB Entry DOI: 10.7270/Q2BK1BGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-chymotrypsin (Homo sapiens (Human)) | BDBM50075114 (1,1-dimethyl-2-phenylcarboxamidooctanoic anhydride...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Steel Corporation Curated by ChEMBL | Assay Description Inhibitory activity against human leukocyte cathepsin G (h-CG) | Bioorg Med Chem Lett 9: 413-8 (1999) BindingDB Entry DOI: 10.7270/Q2BK1BGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-1 (Homo sapiens (Human)) | BDBM50075114 (1,1-dimethyl-2-phenylcarboxamidooctanoic anhydride...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Steel Corporation Curated by ChEMBL | Assay Description Inhibitory activity against porcine pancreatic trypsin (TRP) | Bioorg Med Chem Lett 9: 413-8 (1999) BindingDB Entry DOI: 10.7270/Q2BK1BGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50075114 (1,1-dimethyl-2-phenylcarboxamidooctanoic anhydride...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Steel Corporation Curated by ChEMBL | Assay Description Inhibitory activity against human chymase (h-chymase) | Bioorg Med Chem Lett 9: 413-8 (1999) BindingDB Entry DOI: 10.7270/Q2BK1BGC | |||||||||||
More data for this Ligand-Target Pair |