BDBM50075324 2-(2,6-Diethyl-phenyl)-4-hydroxy-isoindole-1,3-dione::CHEMBL153096

SMILES: CCc1cccc(CC)c1N1C(=O)c2cccc(O)c2C1=O

InChI Key: InChIKey=VAFOPKPKVXACDA-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075324   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Homo sapiens (Human))	BDBM50075324 (2-(2,6-Diethyl-phenyl)-4-hydroxy-isoindole-1,3-dio...) Show SMILES CCc1cccc(CC)c1N1C(=O)c2cccc(O)c2C1=O Show InChI InChI=1S/C18H17NO3/c1-3-11-7-5-8-12(4-2)16(11)19-17(21)13-9-6-10-14(20)15(13)18(19)22/h5-10,20H,3-4H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell line				Bioorg Med Chem Lett 9: 559-62 (1999) BindingDB Entry DOI: 10.7270/Q2ZW1MFX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50075324 (2-(2,6-Diethyl-phenyl)-4-hydroxy-isoindole-1,3-dio...) Show SMILES CCc1cccc(CC)c1N1C(=O)c2cccc(O)c2C1=O Show InChI InChI=1S/C18H17NO3/c1-3-11-7-5-8-12(4-2)16(11)19-17(21)13-9-6-10-14(20)15(13)18(19)22/h5-10,20H,3-4H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell line				Bioorg Med Chem Lett 9: 559-62 (1999) BindingDB Entry DOI: 10.7270/Q2ZW1MFX
					More data for this Ligand-Target Pair
Aminopeptidase (Homo sapiens (Human))	BDBM50075324 (2-(2,6-Diethyl-phenyl)-4-hydroxy-isoindole-1,3-dio...) Show SMILES CCc1cccc(CC)c1N1C(=O)c2cccc(O)c2C1=O Show InChI InChI=1S/C18H17NO3/c1-3-11-7-5-8-12(4-2)16(11)19-17(21)13-9-6-10-14(20)15(13)18(19)22/h5-10,20H,3-4H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell line				Bioorg Med Chem Lett 9: 559-62 (1999) BindingDB Entry DOI: 10.7270/Q2ZW1MFX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50075324 (2-(2,6-Diethyl-phenyl)-4-hydroxy-isoindole-1,3-dio...) Show SMILES CCc1cccc(CC)c1N1C(=O)c2cccc(O)c2C1=O Show InChI InChI=1S/C18H17NO3/c1-3-11-7-5-8-12(4-2)16(11)19-17(21)13-9-6-10-14(20)15(13)18(19)22/h5-10,20H,3-4H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell line				Bioorg Med Chem Lett 9: 559-62 (1999) BindingDB Entry DOI: 10.7270/Q2ZW1MFX
					More data for this Ligand-Target Pair