BDBM50075662 3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclopent-2-enone::CHEMBL23170

SMILES: CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccccc1

InChI Key: InChIKey=UNHXJQNYRJHGEJ-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075662 (3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclopent-2-...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccccc1 |t:11| Show InChI InChI=1S/C18H16O3S/c1-22(20,21)15-9-7-13(8-10-15)16-11-12-17(19)18(16)14-5-3-2-4-6-14/h2-10H,11-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50075662 (3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclopent-2-...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccccc1 |t:11| Show InChI InChI=1S/C18H16O3S/c1-22(20,21)15-9-7-13(8-10-15)16-11-12-17(19)18(16)14-5-3-2-4-6-14/h2-10H,11-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 1 (hCOX-1) in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075662 (3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclopent-2-...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccccc1 |t:11| Show InChI InChI=1S/C18H16O3S/c1-22(20,21)15-9-7-13(8-10-15)16-11-12-17(19)18(16)14-5-3-2-4-6-14/h2-10H,11-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50075662 (3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclopent-2-...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccccc1 |t:11| Show InChI InChI=1S/C18H16O3S/c1-22(20,21)15-9-7-13(8-10-15)16-11-12-17(19)18(16)14-5-3-2-4-6-14/h2-10H,11-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes .				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair