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SMILES: CCOC(=O)C1=C2C3C(C=CC=C3N=C1N1CCN(C)CC1)c1ccccc21

InChI Key: InChIKey=RFOSKYASXJOWGG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50076406   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 3A/3B


(Rattus norvegicus-RAT)		BDBM50076406
PNG
(2-(4-Methyl-piperazin-1-yl)-6a,10c-dihydro-indeno[...)
Show SMILES CCOC(=O)C1=C2C3C(C=CC=C3N=C1N1CCN(C)CC1)c1ccccc21 |c:9,11,14,t:5|
Show InChI InChI=1S/C23H25N3O2/c1-3-28-23(27)21-20-17-8-5-4-7-15(17)16-9-6-10-18(19(16)20)24-22(21)26-13-11-25(2)12-14-26/h4-10,16,19H,3,11-14H2,1-2H3
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PC cid
PC sid
UniChem

Similars
Article
PubMed
 3.90n/an/an/an/an/an/an/an/a



Universit£ di Siena

Curated by ChEMBL


Assay Description
Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissue

J Med Chem 42: 1556-75 (1999)


Article DOI: 10.1021/jm981112s
BindingDB Entry DOI: 10.7270/Q2D50NPW
More data for this
Ligand-Target Pair