BDBM50076700 (6S,8R)-6,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one::CHEMBL268326

SMILES: C[C@@H]1C[C@H](C)c2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F

InChI Key: InChIKey=GQIQHMXROPJXOG-JGVFFNPUSA-N

Data: 1 KI  1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076700   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50076700 ((6S,8R)-6,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tet...) Show SMILES C[C@@H]1C[C@H](C)c2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F Show InChI InChI=1S/C15H15F3N2O/c1-7-3-8(2)19-12-6-13-10(4-9(7)12)11(15(16,17)18)5-14(21)20-13/h4-8,19H,3H2,1-2H3,(H,20,21)/t7-,8+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50076700 ((6S,8R)-6,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tet...) Show SMILES C[C@@H]1C[C@H](C)c2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F Show InChI InChI=1S/C15H15F3N2O/c1-7-3-8(2)19-12-6-13-10(4-9(7)12)11(15(16,17)18)5-14(21)20-13/h4-8,19H,3H2,1-2H3,(H,20,21)/t7-,8+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50076700 ((6S,8R)-6,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tet...) Show SMILES C[C@@H]1C[C@H](C)c2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F Show InChI InChI=1S/C15H15F3N2O/c1-7-3-8(2)19-12-6-13-10(4-9(7)12)11(15(16,17)18)5-14(21)20-13/h4-8,19H,3H2,1-2H3,(H,20,21)/t7-,8+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair