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SMILES: CCN(CC1CC1)c1nc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)c1C

InChI Key: InChIKey=FGIGTXAIHYDNLU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50076782   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50076782
PNG
(CHEMBL10154 | N-Cyclopropylmethyl-N-ethyl-2,5-dime...)
Show SMILES CCN(CC1CC1)c1nc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)c1C
Show InChI InChI=1S/C18H21Cl3N4/c1-4-25(9-12-5-6-12)18-10(2)17(22-11(3)23-18)24-16-14(20)7-13(19)8-15(16)21/h7-8,12H,4-6,9H2,1-3H3,(H,22,23,24)
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PubMed
 2n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Antagonistic activity for Corticotropin releasing factor receptor 1

Bioorg Med Chem Lett 9: 1063-6 (1999)


BindingDB Entry DOI: 10.7270/Q21V5D5N
More data for this
Ligand-Target Pair