null

SMILES: CSCC[C@H](NC(=O)c1ccc(COCc2ccc(o2)-c2ccncc2)cc1-c1ccccc1C)C([O-])=O

InChI Key: InChIKey=LHMOVHABFVYLCF-MHZLTWQESA-M

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076802   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50076802 (CHEMBL10912 | Lithium; (S)-2-{[2'-methyl-5-(5-pyri...) Show SMILES CSCC[C@H](NC(=O)c1ccc(COCc2ccc(o2)-c2ccncc2)cc1-c1ccccc1C)C([O-])=O Show InChI InChI=1S/C30H30N2O5S/c1-20-5-3-4-6-24(20)26-17-21(7-9-25(26)29(33)32-27(30(34)35)13-16-38-2)18-36-19-23-8-10-28(37-23)22-11-14-31-15-12-22/h3-12,14-15,17,27H,13,16,18-19H2,1-2H3,(H,32,33)(H,34,35)/p-1/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)				Bioorg Med Chem Lett 9: 1069-74 (1999) BindingDB Entry DOI: 10.7270/Q2X34WNT
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50076802 (CHEMBL10912 | Lithium; (S)-2-{[2'-methyl-5-(5-pyri...) Show SMILES CSCC[C@H](NC(=O)c1ccc(COCc2ccc(o2)-c2ccncc2)cc1-c1ccccc1C)C([O-])=O Show InChI InChI=1S/C30H30N2O5S/c1-20-5-3-4-6-24(20)26-17-21(7-9-25(26)29(33)32-27(30(34)35)13-16-38-2)18-36-19-23-8-10-28(37-23)22-11-14-31-15-12-22/h3-12,14-15,17,27H,13,16,18-19H2,1-2H3,(H,32,33)(H,34,35)/p-1/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>0.300	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)				Bioorg Med Chem Lett 9: 1069-74 (1999) BindingDB Entry DOI: 10.7270/Q2X34WNT
					More data for this Ligand-Target Pair