null

SMILES: OC(=O)[C@@H](Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc(s1)C#Cc1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=OELFZOQYHXDMPS-HHHXNRCGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50077164 ((R)-3-(1H-Indol-3-yl)-2-[5-(4-phenoxy-phenylethyny...) Show SMILES OC(=O)[C@@H](Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc(s1)C#Cc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C29H22N2O5S2/c32-29(33)27(18-21-19-30-26-9-5-4-8-25(21)26)31-38(34,35)28-17-16-24(37-28)15-12-20-10-13-23(14-11-20)36-22-6-2-1-3-7-22/h1-11,13-14,16-17,19,27,30-31H,18H2,(H,32,33)/t27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)				J Med Chem 42: 1723-38 (1999) Article DOI: 10.1021/jm980514x BindingDB Entry DOI: 10.7270/Q2KP81BQ
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50077164 ((R)-3-(1H-Indol-3-yl)-2-[5-(4-phenoxy-phenylethyny...) Show SMILES OC(=O)[C@@H](Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc(s1)C#Cc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C29H22N2O5S2/c32-29(33)27(18-21-19-30-26-9-5-4-8-25(21)26)31-38(34,35)28-17-16-24(37-28)15-12-20-10-13-23(14-11-20)36-22-6-2-1-3-7-22/h1-11,13-14,16-17,19,27,30-31H,18H2,(H,32,33)/t27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against Matrix metalloproteinase-9 (concentration required for 50% inhibition of enzyme activity)				J Med Chem 42: 1723-38 (1999) Article DOI: 10.1021/jm980514x BindingDB Entry DOI: 10.7270/Q2KP81BQ
					More data for this Ligand-Target Pair