BDBM50077325 2-(3,4-Dihydroxy-phenyl)-7-hydroxy-chromen-4-one::2-(3,4-dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one::3',4',7-trihydroxyflavon::7,3',4'-Trihydroxyflavone::CHEMBL301624

SMILES: Oc1ccc2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1

InChI Key: InChIKey=PVFGJHYLIHMCQD-UHFFFAOYSA-N

Data: 6 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50077325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50077325 (2-(3,4-Dihydroxy-phenyl)-7-hydroxy-chromen-4-one |...) Show SMILES Oc1ccc2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C15H10O5/c16-9-2-3-10-12(18)7-14(20-15(10)6-9)8-1-4-11(17)13(19)5-8/h1-7,16-17,19H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BU-Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase from HEK293 cell extracts by Flash-Plate assay				J Med Chem 47: 6466-75 (2004) Article DOI: 10.1021/jm040810b BindingDB Entry DOI: 10.7270/Q2P55N1R
					More data for this Ligand-Target Pair
Aldose reductase (ALR2) (Bos taurus (Cattle))	BDBM50077325 (2-(3,4-Dihydroxy-phenyl)-7-hydroxy-chromen-4-one |...) Show SMILES Oc1ccc2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C15H10O5/c16-9-2-3-10-12(18)7-14(20-15(10)6-9)8-1-4-11(17)13(19)5-8/h1-7,16-17,19H	PDB GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Modena Curated by ChEMBL					Assay Description Inhibition of ALR2 (aldose reductase) of bovine lens				J Med Chem 42: 1881-93 (1999) Article DOI: 10.1021/jm980441h BindingDB Entry DOI: 10.7270/Q25X29M1
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human))	BDBM50077325 (2-(3,4-Dihydroxy-phenyl)-7-hydroxy-chromen-4-one |...) Show SMILES Oc1ccc2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C15H10O5/c16-9-2-3-10-12(18)7-14(20-15(10)6-9)8-1-4-11(17)13(19)5-8/h1-7,16-17,19H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
University of Oulu Curated by ChEMBL					Assay Description Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assay				J Med Chem 56: 3507-17 (2013) Article DOI: 10.1021/jm3018783 BindingDB Entry DOI: 10.7270/Q24M95W6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50077325 (2-(3,4-Dihydroxy-phenyl)-7-hydroxy-chromen-4-one |...) Show SMILES Oc1ccc2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C15H10O5/c16-9-2-3-10-12(18)7-14(20-15(10)6-9)8-1-4-11(17)13(19)5-8/h1-7,16-17,19H	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oulu Curated by ChEMBL					Assay Description Inhibition of human recombinant ARTD1 by fluorescence assay				J Med Chem 56: 3507-17 (2013) Article DOI: 10.1021/jm3018783 BindingDB Entry DOI: 10.7270/Q24M95W6
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50077325 (2-(3,4-Dihydroxy-phenyl)-7-hydroxy-chromen-4-one |...) Show SMILES Oc1ccc2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C15H10O5/c16-9-2-3-10-12(18)7-14(20-15(10)6-9)8-1-4-11(17)13(19)5-8/h1-7,16-17,19H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
University of Oulu Curated by ChEMBL					Assay Description Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...				J Med Chem 56: 3507-17 (2013) Article DOI: 10.1021/jm3018783 BindingDB Entry DOI: 10.7270/Q24M95W6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50077325 (2-(3,4-Dihydroxy-phenyl)-7-hydroxy-chromen-4-one |...) Show SMILES Oc1ccc2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C15H10O5/c16-9-2-3-10-12(18)7-14(20-15(10)6-9)8-1-4-11(17)13(19)5-8/h1-7,16-17,19H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Porto Curated by ChEMBL					Assay Description Inhibition of 5-LOX-mediated LTB4 production in human neutrophils using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...				Eur J Med Chem 72: 137-45 (2014) Article DOI: 10.1016/j.ejmech.2013.11.030 BindingDB Entry DOI: 10.7270/Q27H1M2P
					More data for this Ligand-Target Pair