BDBM50077387 (R)-2-(4-Butoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide::2-(4-Butoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide::CHEMBL57461

SMILES: CCCCOc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2C[C@@H]1C(=O)NO

InChI Key: InChIKey=GEPDPACRTHVSTD-LJQANCHMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077387   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil collagenase (Homo sapiens (Human))	BDBM50077387 ((R)-2-(4-Butoxy-benzenesulfonyl)-1,2,3,4-tetrahydr...) Show SMILES CCCCOc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2C[C@@H]1C(=O)NO Show InChI InChI=1S/C20H24N2O5S/c1-2-3-12-27-17-8-10-18(11-9-17)28(25,26)22-14-16-7-5-4-6-15(16)13-19(22)20(23)21-24/h4-11,19,24H,2-3,12-14H2,1H3,(H,21,23)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Marion Roussel Curated by ChEMBL					Assay Description Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]				J Med Chem 42: 1908-20 (1999) Article DOI: 10.1021/jm980631s BindingDB Entry DOI: 10.7270/Q2251JV5
					More data for this Ligand-Target Pair