null

SMILES: CNCCOc1cccc2NC(=O)Cc12

InChI Key: InChIKey=STMJSLDMROVPBX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50077567 (4-(2-Methylamino-ethoxy)-1,3-dihydro-indol-2-one |...) Show SMILES CNCCOc1cccc2NC(=O)Cc12 Show InChI InChI=1S/C11H14N2O2/c1-12-5-6-15-10-4-2-3-9-8(10)7-11(14)13-9/h2-4,12H,5-7H2,1H3,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranes				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50077567 (4-(2-Methylamino-ethoxy)-1,3-dihydro-indol-2-one |...) Show SMILES CNCCOc1cccc2NC(=O)Cc12 Show InChI InChI=1S/C11H14N2O2/c1-12-5-6-15-10-4-2-3-9-8(10)7-11(14)13-9/h2-4,12H,5-7H2,1H3,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	147	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranes				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50077567 (4-(2-Methylamino-ethoxy)-1,3-dihydro-indol-2-one |...) Show SMILES CNCCOc1cccc2NC(=O)Cc12 Show InChI InChI=1S/C11H14N2O2/c1-12-5-6-15-10-4-2-3-9-8(10)7-11(14)13-9/h2-4,12H,5-7H2,1H3,(H,13,14)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	276	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenates				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair