null

SMILES: Fc1ccc(OCCN2Cc3ccccc3C2)c2CC(=O)Nc12

InChI Key: InChIKey=AAMLBIYNFUAPCS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50077573 (4-[2-(1,3-Dihydro-isoindol-2-yl)-ethoxy]-7-fluoro-...) Show SMILES Fc1ccc(OCCN2Cc3ccccc3C2)c2CC(=O)Nc12 Show InChI InChI=1S/C18H17FN2O2/c19-15-5-6-16(14-9-17(22)20-18(14)15)23-8-7-21-10-12-3-1-2-4-13(12)11-21/h1-6H,7-11H2,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranes				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50077573 (4-[2-(1,3-Dihydro-isoindol-2-yl)-ethoxy]-7-fluoro-...) Show SMILES Fc1ccc(OCCN2Cc3ccccc3C2)c2CC(=O)Nc12 Show InChI InChI=1S/C18H17FN2O2/c19-15-5-6-16(14-9-17(22)20-18(14)15)23-8-7-21-10-12-3-1-2-4-13(12)11-21/h1-6H,7-11H2,(H,20,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenates				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50077573 (4-[2-(1,3-Dihydro-isoindol-2-yl)-ethoxy]-7-fluoro-...) Show SMILES Fc1ccc(OCCN2Cc3ccccc3C2)c2CC(=O)Nc12 Show InChI InChI=1S/C18H17FN2O2/c19-15-5-6-16(14-9-17(22)20-18(14)15)23-8-7-21-10-12-3-1-2-4-13(12)11-21/h1-6H,7-11H2,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranes				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair