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SMILES: Cc1ccc(CNCCOc2ccc(Cl)c3NC(=O)Cc23)cc1

InChI Key: InChIKey=GZDWJPMFRZBGFX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50077591 (7-Chloro-4-[2-(4-methyl-benzylamino)-ethoxy]-1,3-d...) Show SMILES Cc1ccc(CNCCOc2ccc(Cl)c3NC(=O)Cc23)cc1 Show InChI InChI=1S/C18H19ClN2O2/c1-12-2-4-13(5-3-12)11-20-8-9-23-16-7-6-15(19)18-14(16)10-17(22)21-18/h2-7,20H,8-11H2,1H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranes				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50077591 (7-Chloro-4-[2-(4-methyl-benzylamino)-ethoxy]-1,3-d...) Show SMILES Cc1ccc(CNCCOc2ccc(Cl)c3NC(=O)Cc23)cc1 Show InChI InChI=1S/C18H19ClN2O2/c1-12-2-4-13(5-3-12)11-20-8-9-23-16-7-6-15(19)18-14(16)10-17(22)21-18/h2-7,20H,8-11H2,1H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranes				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50077591 (7-Chloro-4-[2-(4-methyl-benzylamino)-ethoxy]-1,3-d...) Show SMILES Cc1ccc(CNCCOc2ccc(Cl)c3NC(=O)Cc23)cc1 Show InChI InChI=1S/C18H19ClN2O2/c1-12-2-4-13(5-3-12)11-20-8-9-23-16-7-6-15(19)18-14(16)10-17(22)21-18/h2-7,20H,8-11H2,1H3,(H,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenates				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair