BDBM50077593 4-[2-(Benzyl-methyl-amino)-ethoxy]-7-chloro-1,3-dihydro-indol-2-one::CHEMBL59501

SMILES: CN(CCOc1ccc(Cl)c2NC(=O)Cc12)Cc1ccccc1

InChI Key: InChIKey=KNYXWJRBLXUOLM-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077593   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50077593 (4-[2-(Benzyl-methyl-amino)-ethoxy]-7-chloro-1,3-di...) Show SMILES CN(CCOc1ccc(Cl)c2NC(=O)Cc12)Cc1ccccc1 Show InChI InChI=1S/C18H19ClN2O2/c1-21(12-13-5-3-2-4-6-13)9-10-23-16-8-7-15(19)18-14(16)11-17(22)20-18/h2-8H,9-12H2,1H3,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranes				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50077593 (4-[2-(Benzyl-methyl-amino)-ethoxy]-7-chloro-1,3-di...) Show SMILES CN(CCOc1ccc(Cl)c2NC(=O)Cc12)Cc1ccccc1 Show InChI InChI=1S/C18H19ClN2O2/c1-21(12-13-5-3-2-4-6-13)9-10-23-16-8-7-15(19)18-14(16)11-17(22)20-18/h2-8H,9-12H2,1H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenates				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50077593 (4-[2-(Benzyl-methyl-amino)-ethoxy]-7-chloro-1,3-di...) Show SMILES CN(CCOc1ccc(Cl)c2NC(=O)Cc12)Cc1ccccc1 Show InChI InChI=1S/C18H19ClN2O2/c1-21(12-13-5-3-2-4-6-13)9-10-23-16-8-7-15(19)18-14(16)11-17(22)20-18/h2-8H,9-12H2,1H3,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranes				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair