null

SMILES: Fc1ccc(OCCNc2ccc3ccccc3c2)c2CC(=O)Nc12

InChI Key: InChIKey=SHSCMNFGMPWQKM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50077601 (7-Fluoro-4-[2-(naphthalen-2-ylamino)-ethoxy]-1,3-d...) Show SMILES Fc1ccc(OCCNc2ccc3ccccc3c2)c2CC(=O)Nc12 Show InChI InChI=1S/C20H17FN2O2/c21-17-7-8-18(16-12-19(24)23-20(16)17)25-10-9-22-15-6-5-13-3-1-2-4-14(13)11-15/h1-8,11,22H,9-10,12H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranes				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50077601 (7-Fluoro-4-[2-(naphthalen-2-ylamino)-ethoxy]-1,3-d...) Show SMILES Fc1ccc(OCCNc2ccc3ccccc3c2)c2CC(=O)Nc12 Show InChI InChI=1S/C20H17FN2O2/c21-17-7-8-18(16-12-19(24)23-20(16)17)25-10-9-22-15-6-5-13-3-1-2-4-14(13)11-15/h1-8,11,22H,9-10,12H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranes				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50077601 (7-Fluoro-4-[2-(naphthalen-2-ylamino)-ethoxy]-1,3-d...) Show SMILES Fc1ccc(OCCNc2ccc3ccccc3c2)c2CC(=O)Nc12 Show InChI InChI=1S/C20H17FN2O2/c21-17-7-8-18(16-12-19(24)23-20(16)17)25-10-9-22-15-6-5-13-3-1-2-4-14(13)11-15/h1-8,11,22H,9-10,12H2,(H,23,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	121	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenates				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair