BDBM50077742 2-Amino-N-{(S)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butylcarbamoyl]-2-cyclohexyl-ethyl}-nicotinamide::CHEMBL282733

SMILES: NC(=N)NCCC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cccnc1N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key: InChIKey=KDCHTINFDXNROA-HJOGWXRNSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077742   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50077742 (2-Amino-N-{(S)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-...) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cccnc1N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C30H43N9O4/c31-25-21(13-7-15-35-25)27(41)39-24(18-20-11-5-2-6-12-20)29(43)37-22(14-8-16-36-30(33)34)28(42)38-23(26(32)40)17-19-9-3-1-4-10-19/h1,3-4,7,9-10,13,15,20,22-24H,2,5-6,8,11-12,14,16-18H2,(H2,31,35)(H2,32,40)(H,37,43)(H,38,42)(H,39,41)(H4,33,34,36)/t22-,23-,24-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to thrombin receptor (PAR-1) on membranes from CHRF cells				Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP
					More data for this Ligand-Target Pair
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50077742 (2-Amino-N-{(S)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-...) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cccnc1N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C30H43N9O4/c31-25-21(13-7-15-35-25)27(41)39-24(18-20-11-5-2-6-12-20)29(43)37-22(14-8-16-36-30(33)34)28(42)38-23(26(32)40)17-19-9-3-1-4-10-19/h1,3-4,7,9-10,13,15,20,22-24H,2,5-6,8,11-12,14,16-18H2,(H2,31,35)(H2,32,40)(H,37,43)(H,38,42)(H,39,41)(H4,33,34,36)/t22-,23-,24-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin				Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP
					More data for this Ligand-Target Pair