BDBM50077910 CHEMBL3417233

SMILES: COc1cc2C(CC(C)c2cc1Br)N[C@@H]1CC[C@](C1)(C(C)C)C(=O)N1CCc2ccc(cc2C1)C(F)(F)F

InChI Key: InChIKey=UXFGCCXECAOESJ-PHZQMMEXSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077910   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50077910 (CHEMBL3417233) Show SMILES COc1cc2C(CC(C)c2cc1Br)N[C@@H]1CC[C@](C1)(C(C)C)C(=O)N1CCc2ccc(cc2C1)C(F)(F)F |r| Show InChI InChI=1S/C30H36BrF3N2O2/c1-17(2)29(28(37)36-10-8-19-5-6-21(30(32,33)34)12-20(19)16-36)9-7-22(15-29)35-26-11-18(3)23-13-25(31)27(38-4)14-24(23)26/h5-6,12-14,17-18,22,26,35H,7-11,15-16H2,1-4H3/t18?,22-,26?,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of 0.1 nM [125I]CCL2 from human CCR2 expressing human U2OS cell membrane by scintillation spectrometry				Eur J Med Chem 93: 121-34 (2015) Article DOI: 10.1016/j.ejmech.2015.01.063 BindingDB Entry DOI: 10.7270/Q25M67DX
					More data for this Ligand-Target Pair