BDBM50078206 CHEMBL2153135

SMILES: COc1ccc2\C(=C/c3cc(OC)c(OC)c(OC)c3)C(=O)CCc2c1

InChI Key: InChIKey=CCAWGLJBUQKREZ-RQZCQDPDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain (Sus scrofa)	BDBM50078206 (CHEMBL2153135) Show SMILES COc1ccc2\C(=C/c3cc(OC)c(OC)c(OC)c3)C(=O)CCc2c1 Show InChI InChI=1S/C21H22O5/c1-23-15-6-7-16-14(12-15)5-8-18(22)17(16)9-13-10-19(24-2)21(26-4)20(11-13)25-3/h6-7,9-12H,5,8H2,1-4H3/b17-9+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of porcine brain tubulin assembly measured every 1 min for 60 mins by turbidimetric analysis				J Med Chem 55: 5720-33 (2012) Article DOI: 10.1021/jm300596s BindingDB Entry DOI: 10.7270/Q2Z89G8V
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50078206 (CHEMBL2153135) Show SMILES COc1ccc2\C(=C/c3cc(OC)c(OC)c(OC)c3)C(=O)CCc2c1 Show InChI InChI=1S/C21H22O5/c1-23-15-6-7-16-14(12-15)5-8-18(22)17(16)9-13-10-19(24-2)21(26-4)20(11-13)25-3/h6-7,9-12H,5,8H2,1-4H3/b17-9+	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization incubated for 60 mins by microplate reader based turbidimetry				J Med Chem 58: 2538-46 (2015) Article DOI: 10.1021/acs.jmedchem.5b00118 BindingDB Entry DOI: 10.7270/Q24M966N
					More data for this Ligand-Target Pair