BDBM50078235 2-(2,4-Dichloro-phenyl)-5-(2-methoxy-phenyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid 2-dimethylamino-ethyl ester::CHEMBL290416

SMILES: COc1ccccc1C1N2C=C(SC2=NC(C)=C1C(=O)OCCN(C)C)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=HDWTUYRDCPHOSH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50078235   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50078235 (2-(2,4-Dichloro-phenyl)-5-(2-methoxy-phenyl)-7-met...) Show SMILES COc1ccccc1C1N2C=C(SC2=NC(C)=C1C(=O)OCCN(C)C)c1ccc(Cl)cc1Cl |c:11,15,18| Show InChI InChI=1S/C25H25Cl2N3O3S/c1-15-22(24(31)33-12-11-29(2)3)23(18-7-5-6-8-20(18)32-4)30-14-21(34-25(30)28-15)17-10-9-16(26)13-19(17)27/h5-10,13-14,23H,11-12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of 1S,3R-ACPD (10 microM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cells				Bioorg Med Chem Lett 9: 1573-6 (1999) BindingDB Entry DOI: 10.7270/Q2XS5TKC
					More data for this Ligand-Target Pair