BDBM50078337 6-(4-Hexyl-phenylamino)-1-(2-methoxy-ethyl)-1H-pyrimidine-2,4-dione::CHEMBL77919

SMILES: CCCCCCc1ccc(Nc2cc(=O)[nH]c(=O)n2CCOC)cc1

InChI Key: InChIKey=NXKHBUOIWJMVDL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50078337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uracil-DNA glycosylase (UNG) (Homo sapiens (Human))	BDBM50078337 (6-(4-Hexyl-phenylamino)-1-(2-methoxy-ethyl)-1H-pyr...) Show SMILES CCCCCCc1ccc(Nc2cc(=O)[nH]c(=O)n2CCOC)cc1 Show InChI InChI=1S/C19H27N3O3/c1-3-4-5-6-7-15-8-10-16(11-9-15)20-17-14-18(23)21-19(24)22(17)12-13-25-2/h8-11,14,20H,3-7,12-13H2,1-2H3,(H,21,23,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Medical Center Curated by ChEMBL					Assay Description Inhibitory potency of the compound against HSV-1 UDG (Herpes Simplex virus type-I Uracil DNA glycosylase)				J Med Chem 42: 2344-50 (1999) Article DOI: 10.1021/jm980718d BindingDB Entry DOI: 10.7270/Q21J98ZQ
					More data for this Ligand-Target Pair