BDBM50078399 (S)-1-((3R,4S)-4-Amino-3-hydroxy-6-methyl-heptanoyl)-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-ethyl)-amide::CHEMBL78482

SMILES: CC(C)C[C@H](N)[C@H](O)CC(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O

InChI Key: InChIKey=FRDYHGMXWCWIGC-ZDEQEGDKSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50078399   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine aminopeptidase (Homo sapiens (Human))	BDBM50078399 ((S)-1-((3R,4S)-4-Amino-3-hydroxy-6-methyl-heptanoy...) Show SMILES CC(C)C[C@H](N)[C@H](O)CC(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O Show InChI InChI=1S/C16H30N4O4/c1-9(2)7-11(17)13(21)8-14(22)20-6-4-5-12(20)16(24)19-10(3)15(18)23/h9-13,21H,4-8,17H2,1-3H3,(H2,18,23)(H,19,24)/t10-,11-,12-,13+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia and Upjohn Curated by ChEMBL					Assay Description Inhibition against Leucyl aminopeptidase from pig kidney.				J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS
					More data for this Ligand-Target Pair
Membrane-bound aminopeptidase P (APP2) (Homo sapiens (Human))	BDBM50078399 ((S)-1-((3R,4S)-4-Amino-3-hydroxy-6-methyl-heptanoy...) Show SMILES CC(C)C[C@H](N)[C@H](O)CC(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O Show InChI InChI=1S/C16H30N4O4/c1-9(2)7-11(17)13(21)8-14(22)20-6-4-5-12(20)16(24)19-10(3)15(18)23/h9-13,21H,4-8,17H2,1-3H3,(H2,18,23)(H,19,24)/t10-,11-,12-,13+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia and Upjohn Curated by ChEMBL					Assay Description Inhibition against membrane bound human aminopeptidase P				J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS
					More data for this Ligand-Target Pair
Xaa-Pro aminopeptidase 1 (Homo sapiens (Human))	BDBM50078399 ((S)-1-((3R,4S)-4-Amino-3-hydroxy-6-methyl-heptanoy...) Show SMILES CC(C)C[C@H](N)[C@H](O)CC(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O Show InChI InChI=1S/C16H30N4O4/c1-9(2)7-11(17)13(21)8-14(22)20-6-4-5-12(20)16(24)19-10(3)15(18)23/h9-13,21H,4-8,17H2,1-3H3,(H2,18,23)(H,19,24)/t10-,11-,12-,13+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia and Upjohn Curated by ChEMBL					Assay Description Inhibition against cytosolic Aminopeptidase P from human heart.				J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS
					More data for this Ligand-Target Pair
Xaa-Pro aminopeptidase 2 (Rattus norvegicus)	BDBM50078399 ((S)-1-((3R,4S)-4-Amino-3-hydroxy-6-methyl-heptanoy...) Show SMILES CC(C)C[C@H](N)[C@H](O)CC(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O Show InChI InChI=1S/C16H30N4O4/c1-9(2)7-11(17)13(21)8-14(22)20-6-4-5-12(20)16(24)19-10(3)15(18)23/h9-13,21H,4-8,17H2,1-3H3,(H2,18,23)(H,19,24)/t10-,11-,12-,13+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+6	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia and Upjohn Curated by ChEMBL					Assay Description Activity against membrane bound rat aminopeptidase P				J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS
					More data for this Ligand-Target Pair
Xaa-Pro dipeptidase (Homo sapiens (Human))	BDBM50078399 ((S)-1-((3R,4S)-4-Amino-3-hydroxy-6-methyl-heptanoy...) Show SMILES CC(C)C[C@H](N)[C@H](O)CC(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O Show InChI InChI=1S/C16H30N4O4/c1-9(2)7-11(17)13(21)8-14(22)20-6-4-5-12(20)16(24)19-10(3)15(18)23/h9-13,21H,4-8,17H2,1-3H3,(H2,18,23)(H,19,24)/t10-,11-,12-,13+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia and Upjohn Curated by ChEMBL					Assay Description Inhibition against Prolidase from pig kidney.				J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS
					More data for this Ligand-Target Pair
Membrane-bound aminopeptidase P (APP2) (Homo sapiens (Human))	BDBM50078399 ((S)-1-((3R,4S)-4-Amino-3-hydroxy-6-methyl-heptanoy...) Show SMILES CC(C)C[C@H](N)[C@H](O)CC(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O Show InChI InChI=1S/C16H30N4O4/c1-9(2)7-11(17)13(21)8-14(22)20-6-4-5-12(20)16(24)19-10(3)15(18)23/h9-13,21H,4-8,17H2,1-3H3,(H2,18,23)(H,19,24)/t10-,11-,12-,13+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia and Upjohn Curated by ChEMBL					Assay Description Inhibition against membrane bound monkey aminopeptidase P				J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS
					More data for this Ligand-Target Pair