BDBM50078528 7-Chloro-5-ethyl-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxaline-2-carboxylic acid::CHEMBL315484

SMILES: CCn1c2cc(Cl)ccc2n2nc(nc2c1=O)C(O)=O

InChI Key: InChIKey=OLADZCCQHZHLFC-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078528   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078528 (7-Chloro-5-ethyl-4-oxo-4,5-dihydro-[1,2,4]triazolo...) Show SMILES CCn1c2cc(Cl)ccc2n2nc(nc2c1=O)C(O)=O Show InChI InChI=1S/C12H9ClN4O3/c1-2-16-8-5-6(13)3-4-7(8)17-10(11(16)18)14-9(15-17)12(19)20/h3-5H,2H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Binding affinity towards N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes using [3H]-glycine as radioligand				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078528 (7-Chloro-5-ethyl-4-oxo-4,5-dihydro-[1,2,4]triazolo...) Show SMILES CCn1c2cc(Cl)ccc2n2nc(nc2c1=O)C(O)=O Show InChI InChI=1S/C12H9ClN4O3/c1-2-16-8-5-6(13)3-4-7(8)17-10(11(16)18)14-9(15-17)12(19)20/h3-5H,2H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.89E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Moscow State University Curated by ChEMBL					Assay Description Binding selectivity towards N-methyl-D-aspartate glutamate receptor 1 was determined by using [3H]- glycine/NMDA				J Med Chem 46: 4063-9 (2003) Article DOI: 10.1021/jm030833a BindingDB Entry DOI: 10.7270/Q2445KVC
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078528 (7-Chloro-5-ethyl-4-oxo-4,5-dihydro-[1,2,4]triazolo...) Show SMILES CCn1c2cc(Cl)ccc2n2nc(nc2c1=O)C(O)=O Show InChI InChI=1S/C12H9ClN4O3/c1-2-16-8-5-6(13)3-4-7(8)17-10(11(16)18)14-9(15-17)12(19)20/h3-5H,2H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair