BDBM50078536 7-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxaline-2-carboxylic acid ethyl ester::CHEMBL83919::ethyl 7-chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxaline-2-carboxylate

SMILES: CCOC(=O)c1nc2n(n1)c1ccc(Cl)cc1[nH]c2=O

InChI Key: InChIKey=DXAANXIRAMZBPL-UHFFFAOYSA-N

Data: 3 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50078536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50078536 (7-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]q...) Show SMILES CCOC(=O)c1nc2n(n1)c1ccc(Cl)cc1[nH]c2=O Show InChI InChI=1S/C12H9ClN4O3/c1-2-20-12(19)9-15-10-11(18)14-7-5-6(13)3-4-8(7)17(10)16-9/h3-5H,2H2,1H3,(H,14,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells				J Med Chem 48: 7932-45 (2005) Article DOI: 10.1021/jm0504149 BindingDB Entry DOI: 10.7270/Q20V8CCR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078536 (7-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]q...) Show SMILES CCOC(=O)c1nc2n(n1)c1ccc(Cl)cc1[nH]c2=O Show InChI InChI=1S/C12H9ClN4O3/c1-2-20-12(19)9-15-10-11(18)14-7-5-6(13)3-4-8(7)17(10)16-9/h3-5H,2H2,1H3,(H,14,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Binding affinity towards N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes using [3H]-glycine as radioligand				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078536 (7-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]q...) Show SMILES CCOC(=O)c1nc2n(n1)c1ccc(Cl)cc1[nH]c2=O Show InChI InChI=1S/C12H9ClN4O3/c1-2-20-12(19)9-15-10-11(18)14-7-5-6(13)3-4-8(7)17(10)16-9/h3-5H,2H2,1H3,(H,14,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Moscow State University Curated by ChEMBL					Assay Description Binding selectivity towards N-methyl-D-aspartate glutamate receptor 1 was determined by using [3H]- glycine/NMDA				J Med Chem 46: 4063-9 (2003) Article DOI: 10.1021/jm030833a BindingDB Entry DOI: 10.7270/Q2445KVC
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078536 (7-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]q...) Show SMILES CCOC(=O)c1nc2n(n1)c1ccc(Cl)cc1[nH]c2=O Show InChI InChI=1S/C12H9ClN4O3/c1-2-20-12(19)9-15-10-11(18)14-7-5-6(13)3-4-8(7)17(10)16-9/h3-5H,2H2,1H3,(H,14,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.21E+4	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair