BDBM50078659 Biphenyl-2-carboxylic acid [5-(5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepine-10-carbonyl)-pyridin-2-yl]-amide::CHEMBL297705

SMILES: O=C(Nc1ccc(cn1)C(=O)N1Cc2cccn2Cc2ccccc12)c1ccccc1-c1ccccc1

InChI Key: InChIKey=NCQQBBAXLMVSOY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V2 Receptor (Rattus norvegicus (Rat))	BDBM50078659 (Biphenyl-2-carboxylic acid [5-(5H,11H-benzo[e]pyrr...) Show SMILES O=C(Nc1ccc(cn1)C(=O)N1Cc2cccn2Cc2ccccc12)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C31H24N4O2/c36-30(27-14-6-5-13-26(27)22-9-2-1-3-10-22)33-29-17-16-23(19-32-29)31(37)35-21-25-12-8-18-34(25)20-24-11-4-7-15-28(24)35/h1-19H,20-21H2,(H,32,33,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Displacement of P[3H]-AVP from isolated rat kidney medullary V2 receptor				Bioorg Med Chem Lett 9: 1737-40 (1999) BindingDB Entry DOI: 10.7270/Q23B5ZBZ
					More data for this Ligand-Target Pair
AVPR1A (RAT)	BDBM50078659 (Biphenyl-2-carboxylic acid [5-(5H,11H-benzo[e]pyrr...) Show SMILES O=C(Nc1ccc(cn1)C(=O)N1Cc2cccn2Cc2ccccc12)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C31H24N4O2/c36-30(27-14-6-5-13-26(27)22-9-2-1-3-10-22)33-29-17-16-23(19-32-29)31(37)35-21-25-12-8-18-34(25)20-24-11-4-7-15-28(24)35/h1-19H,20-21H2,(H,32,33,36)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Displacement of (Phe-3,4,5 [3H]-) AVP from isolated rat hepatic V1a receptor				Bioorg Med Chem Lett 9: 1737-40 (1999) BindingDB Entry DOI: 10.7270/Q23B5ZBZ
					More data for this Ligand-Target Pair