BDBM50078806 CHEMBL301202::N,N-dimethyl-5-(phenylsulfamoyl)-2,3-dihydro-1H-indole-1-carboxamide

SMILES: CN(C)C(=O)N1CCc2cc(ccc12)S(=O)(=O)Nc1ccccc1

InChI Key: InChIKey=XXXITHRFEANWNW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078806   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50078806 (CHEMBL301202 | N,N-dimethyl-5-(phenylsulfamoyl)-2,...) Show SMILES CN(C)C(=O)N1CCc2cc(ccc12)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C17H19N3O3S/c1-19(2)17(21)20-11-10-13-12-15(8-9-16(13)20)24(22,23)18-14-6-4-3-5-7-14/h3-9,12,18H,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards cloned human beta-1 adrenergic receptor using [125I]-iodocyanopindolol as radioligand to stimulate increase in cAMP...				Bioorg Med Chem Lett 9: 1869-74 (1999) BindingDB Entry DOI: 10.7270/Q2FN15D1
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50078806 (CHEMBL301202 | N,N-dimethyl-5-(phenylsulfamoyl)-2,...) Show SMILES CN(C)C(=O)N1CCc2cc(ccc12)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C17H19N3O3S/c1-19(2)17(21)20-11-10-13-12-15(8-9-16(13)20)24(22,23)18-14-6-4-3-5-7-14/h3-9,12,18H,10-11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards cloned human beta-2 adrenergic receptor using [125I]-iodocyanopindolol as radioligand to stimulate increase in cAMP...				Bioorg Med Chem Lett 9: 1869-74 (1999) BindingDB Entry DOI: 10.7270/Q2FN15D1
					More data for this Ligand-Target Pair