BDBM50079403 CHEMBL3417207

SMILES: Cc1c(sc2ncnc(Nc3ccc(=O)n(C)c3)c12)C(O)=O

InChI Key: InChIKey=VFTFTXKIPLEFNR-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079403   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50079403 (CHEMBL3417207) Show SMILES Cc1c(sc2ncnc(Nc3ccc(=O)n(C)c3)c12)C(O)=O Show InChI InChI=1S/C14H12N4O3S/c1-7-10-12(17-8-3-4-9(19)18(2)5-8)15-6-16-13(10)22-11(7)14(20)21/h3-6H,1-2H3,(H,20,21)(H,15,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of Mnk2 (unknown origin) pre-incubated for 10 mins before eIF4E peptide substrate addition by ADP-Glo kinase assay				Eur J Med Chem 95: 116-26 (2015) Article DOI: 10.1016/j.ejmech.2015.03.032 BindingDB Entry DOI: 10.7270/Q28917K3
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50079403 (CHEMBL3417207) Show SMILES Cc1c(sc2ncnc(Nc3ccc(=O)n(C)c3)c12)C(O)=O Show InChI InChI=1S/C14H12N4O3S/c1-7-10-12(17-8-3-4-9(19)18(2)5-8)15-6-16-13(10)22-11(7)14(20)21/h3-6H,1-2H3,(H,20,21)(H,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of Mnk1 (unknown origin) pre-incubated for 10 mins before eIF4E peptide substrate addition by ADP-Glo kinase assay				Eur J Med Chem 95: 116-26 (2015) Article DOI: 10.1016/j.ejmech.2015.03.032 BindingDB Entry DOI: 10.7270/Q28917K3
					More data for this Ligand-Target Pair