BDBM50079415 Ac-Tyr-Lys-Trp-Trp-Leu-Arg-Arg-D-Ala-Arg-Pro-Lys-NH2::CHEMBL412248
SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O
InChI Key: InChIKey=BRVWVZJLUPHDEY-PPYNJGRRSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50079415 (Ac-Tyr-Lys-Trp-Trp-Leu-Arg-Arg-D-Ala-Arg-Pro-Lys-N...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description The compound was tested for binding affinity against Opioid receptor kappa 1 by using [3H]Diprenorphine as a radioligand | J Med Chem 42: 3011-3 (1999) Article DOI: 10.1021/jm9901071 BindingDB Entry DOI: 10.7270/Q2N58KKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50079415 (Ac-Tyr-Lys-Trp-Trp-Leu-Arg-Arg-D-Ala-Arg-Pro-Lys-N...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description The compound was tested for binding affinity against Opioid receptor mu 1 by using [3H]DAMGO as a radioligand | J Med Chem 42: 3011-3 (1999) Article DOI: 10.1021/jm9901071 BindingDB Entry DOI: 10.7270/Q2N58KKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50079415 (Ac-Tyr-Lys-Trp-Trp-Leu-Arg-Arg-D-Ala-Arg-Pro-Lys-N...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description The compound was tested for binding affinity against Opioid receptor delta 1 by using [3H]- DPDPE as a radioligand | J Med Chem 42: 3011-3 (1999) Article DOI: 10.1021/jm9901071 BindingDB Entry DOI: 10.7270/Q2N58KKX | |||||||||||
More data for this Ligand-Target Pair |