BDBM50079553 CHEMBL3417477

SMILES: CCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3ccc(F)cc23)c1

InChI Key: InChIKey=LMYTZOVTGRVWCF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50079553 (CHEMBL3417477) Show SMILES CCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3ccc(F)cc23)c1 Show InChI InChI=1S/C22H19FN4O3/c1-2-30-22(29)24-18-5-3-4-15(12-18)14-27-21(28)9-8-20(25-27)26-11-10-16-6-7-17(23)13-19(16)26/h3-13H,2,14H2,1H3,(H,24,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method				Eur J Med Chem 95: 302-12 (2015) Article DOI: 10.1016/j.ejmech.2015.03.041 BindingDB Entry DOI: 10.7270/Q2GQ70G4
					More data for this Ligand-Target Pair