BDBM50079753 7-(4-Isopropyl-benzyl)-N*3*-methyl-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine::CHEMBL305329

SMILES: CNc1nc(N)c2c3ccn(Cc4ccc(cc4)C(C)C)c3ccc2n1

InChI Key: InChIKey=VKTJQQJDOPRDEO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079753   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50079753 (7-(4-Isopropyl-benzyl)-N*3*-methyl-7H-pyrrolo[3,2-...) Show SMILES CNc1nc(N)c2c3ccn(Cc4ccc(cc4)C(C)C)c3ccc2n1 Show InChI InChI=1S/C21H23N5/c1-13(2)15-6-4-14(5-7-15)12-26-11-10-16-18(26)9-8-17-19(16)20(22)25-21(23-3)24-17/h4-11,13H,12H2,1-3H3,(H3,22,23,24,25)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)				Bioorg Med Chem Lett 9: 2073-8 (1999) BindingDB Entry DOI: 10.7270/Q25X284B
					More data for this Ligand-Target Pair