BDBM50079755 7-(4-Isopropyl-benzyl)-3-piperidin-1-yl-7H-pyrrolo[3,2-f]quinazolin-1-ylamine::CHEMBL291807

SMILES: CC(C)c1ccc(Cn2ccc3c2ccc2nc(nc(N)c32)N2CCCCC2)cc1

InChI Key: InChIKey=JRWGUBBGUUMEMX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50079755 (7-(4-Isopropyl-benzyl)-3-piperidin-1-yl-7H-pyrrolo...) Show SMILES CC(C)c1ccc(Cn2ccc3c2ccc2nc(nc(N)c32)N2CCCCC2)cc1 Show InChI InChI=1S/C25H29N5/c1-17(2)19-8-6-18(7-9-19)16-30-15-12-20-22(30)11-10-21-23(20)24(26)28-25(27-21)29-13-4-3-5-14-29/h6-12,15,17H,3-5,13-14,16H2,1-2H3,(H2,26,27,28)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)				Bioorg Med Chem Lett 9: 2073-8 (1999) BindingDB Entry DOI: 10.7270/Q25X284B
					More data for this Ligand-Target Pair