BDBM50079756 7-(4-Isopropyl-benzyl)-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine::CHEMBL292089

SMILES: CC(C)c1ccc(Cn2ccc3c2ccc2nc(N)nc(N)c32)cc1

InChI Key: InChIKey=WSUIAKBTZKKHKW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079756   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50079756 (7-(4-Isopropyl-benzyl)-7H-pyrrolo[3,2-f]quinazolin...) Show SMILES CC(C)c1ccc(Cn2ccc3c2ccc2nc(N)nc(N)c32)cc1 Show InChI InChI=1S/C20H21N5/c1-12(2)14-5-3-13(4-6-14)11-25-10-9-15-17(25)8-7-16-18(15)19(21)24-20(22)23-16/h3-10,12H,11H2,1-2H3,(H4,21,22,23,24)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health& Science University Curated by ChEMBL					Assay Description Antagonist activity at PAR1 (unknown origin) assessed as inhibition of thrombin-induced platelet aggregation				Medchemcomm 6: 510-520 (2015) BindingDB Entry DOI: 10.7270/Q2QN68NS
					More data for this Ligand-Target Pair
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50079756 (7-(4-Isopropyl-benzyl)-7H-pyrrolo[3,2-f]quinazolin...) Show SMILES CC(C)c1ccc(Cn2ccc3c2ccc2nc(N)nc(N)c32)cc1 Show InChI InChI=1S/C20H21N5/c1-12(2)14-5-3-13(4-6-14)11-25-10-9-15-17(25)8-7-16-18(15)19(21)24-20(22)23-16/h3-10,12H,11H2,1-2H3,(H4,21,22,23,24)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)				Bioorg Med Chem Lett 9: 2073-8 (1999) BindingDB Entry DOI: 10.7270/Q25X284B
					More data for this Ligand-Target Pair