BDBM50079757 7-(4-Isopropyl-benzyl)-N*3*,N*3*-dimethyl-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine::CHEMBL416862

SMILES: CC(C)c1ccc(Cn2ccc3c2ccc2nc(nc(N)c32)N(C)C)cc1

InChI Key: InChIKey=ZMUBNANBKAGODS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50079757 (7-(4-Isopropyl-benzyl)-N*3*,N*3*-dimethyl-7H-pyrro...) Show SMILES CC(C)c1ccc(Cn2ccc3c2ccc2nc(nc(N)c32)N(C)C)cc1 Show InChI InChI=1S/C22H25N5/c1-14(2)16-7-5-15(6-8-16)13-27-12-11-17-19(27)10-9-18-20(17)21(23)25-22(24-18)26(3)4/h5-12,14H,13H2,1-4H3,(H2,23,24,25)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)				Bioorg Med Chem Lett 9: 2073-8 (1999) BindingDB Entry DOI: 10.7270/Q25X284B
					More data for this Ligand-Target Pair