BDBM50079761 2-[1-Amino-7-(4-isopropyl-benzyl)-7H-pyrrolo[3,2-f]quinazolin-3-ylamino]-ethanol::CHEMBL302226

SMILES: CC(C)c1ccc(Cn2ccc3c2ccc2nc(NCCO)nc(N)c32)cc1

InChI Key: InChIKey=YDEKMSOWUGUJNG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50079761 (2-[1-Amino-7-(4-isopropyl-benzyl)-7H-pyrrolo[3,2-f...) Show SMILES CC(C)c1ccc(Cn2ccc3c2ccc2nc(NCCO)nc(N)c32)cc1 Show InChI InChI=1S/C22H25N5O/c1-14(2)16-5-3-15(4-6-16)13-27-11-9-17-19(27)8-7-18-20(17)21(23)26-22(25-18)24-10-12-28/h3-9,11,14,28H,10,12-13H2,1-2H3,(H3,23,24,25,26)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)				Bioorg Med Chem Lett 9: 2073-8 (1999) BindingDB Entry DOI: 10.7270/Q25X284B
					More data for this Ligand-Target Pair