BDBM50079763 7-(4-Isopropyl-benzyl)-N*1*,N*3*,N*3*-trimethyl-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine::CHEMBL303084

SMILES: CNc1nc(nc2ccc3n(Cc4ccc(cc4)C(C)C)ccc3c12)N(C)C

InChI Key: InChIKey=WRGIOZQVFSODHP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50079763 (7-(4-Isopropyl-benzyl)-N*1*,N*3*,N*3*-trimethyl-7H...) Show SMILES CNc1nc(nc2ccc3n(Cc4ccc(cc4)C(C)C)ccc3c12)N(C)C Show InChI InChI=1S/C23H27N5/c1-15(2)17-8-6-16(7-9-17)14-28-13-12-18-20(28)11-10-19-21(18)22(24-3)26-23(25-19)27(4)5/h6-13,15H,14H2,1-5H3,(H,24,25,26)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)				Bioorg Med Chem Lett 9: 2073-8 (1999) BindingDB Entry DOI: 10.7270/Q25X284B
					More data for this Ligand-Target Pair