BDBM50079810 2-[1-[5-amino-2-isopropyl-6-sulfanyl-(2S,3E,5R)-3-hexenyl]-4-phenoxy-(2S,4S)-tetrahydro-1H-2-pyrrolylcarboxamido]-4-methylsulfanyl-(2S)-butanoic acid with di( TFA)::CHEMBL67663

SMILES: CSCC[C@H](NC(=O)[C@@H]1C[C@@H](CN1C[C@H](\C=C\[C@@H](N)CS)C(C)C)Oc1ccccc1)C(O)=O

InChI Key: InChIKey=NWNLGHVZFIYUBN-NCELGYRZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079810   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Bos taurus (bovine))	BDBM50079810 (2-[1-[5-amino-2-isopropyl-6-sulfanyl-(2S,3E,5R)-3-...) Show SMILES CSCC[C@H](NC(=O)[C@@H]1C[C@@H](CN1C[C@H](\C=C\[C@@H](N)CS)C(C)C)Oc1ccccc1)C(O)=O Show InChI InChI=1S/C25H39N3O4S2/c1-17(2)18(9-10-19(26)16-33)14-28-15-21(32-20-7-5-4-6-8-20)13-23(28)24(29)27-22(25(30)31)11-12-34-3/h4-10,17-19,21-23,33H,11-16,26H2,1-3H3,(H,27,29)(H,30,31)/b10-9+/t18-,19+,21-,22-,23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras protein				Bioorg Med Chem Lett 9: 2095-100 (1999) BindingDB Entry DOI: 10.7270/Q2Z038PQ
					More data for this Ligand-Target Pair
Geranylgeranyl Transferase (GGTase-I) (Bos taurus (bovine))	BDBM50079810 (2-[1-[5-amino-2-isopropyl-6-sulfanyl-(2S,3E,5R)-3-...) Show SMILES CSCC[C@H](NC(=O)[C@@H]1C[C@@H](CN1C[C@H](\C=C\[C@@H](N)CS)C(C)C)Oc1ccccc1)C(O)=O Show InChI InChI=1S/C25H39N3O4S2/c1-17(2)18(9-10-19(26)16-33)14-28-15-21(32-20-7-5-4-6-8-20)13-23(28)24(29)27-22(25(30)31)11-12-34-3/h4-10,17-19,21-23,33H,11-16,26H2,1-3H3,(H,27,29)(H,30,31)/b10-9+/t18-,19+,21-,22-,23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL protein				Bioorg Med Chem Lett 9: 2095-100 (1999) BindingDB Entry DOI: 10.7270/Q2Z038PQ
					More data for this Ligand-Target Pair